Tissue expression
Cell line expression
Protein structure
ERAP2
Endoplasmic reticulum aminopeptidase 2L-RAP, LRAP
This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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| NSJ Bioreagents | Polyclonal |
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| Proteintech Group | Polyclonal |
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| LSBio | Polyclonal |
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| FineTest Biotech | Polyclonal |
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| Biorbyt | Polyclonal |
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